EFFECTS OF ADMINISTRATION OF VITAMIN-D ON PATIENTS WITH SICKLE-CELL DISEASE

Authors
PRATICO G CALTABIANO L SAMPERI P PALANO GM SCHILIRO G
Citation
G. Pratico et al., EFFECTS OF ADMINISTRATION OF VITAMIN-D ON PATIENTS WITH SICKLE-CELL DISEASE, International journal of pediatric hematology/oncology, 4(2), 1997, pp. 127-130
Citations number
7
Categorie Soggetti
Oncology,Pediatrics,Hematology
Journal title
International journal of pediatric hematology/oncology → ACNP
ISSN journal
10702903
Volume
4
Issue
2
Year of publication
1997
Pages
127 - 130
Database
ISI
SICI code
1070-2903(1997)4:2<127:EOAOVO>2.0.ZU;2-1
Abstract
Changes in bone metabolism in 8 sickle cell disease patients with prev iously documented low serum levels of 25-hydroxyvitamin D were monitor ed. Treatment with this metabolite of vitamin D caused a significant i ncrease in serum levels of osteocalcin and a decrease in serum telopep tide of type I collagen, demonstrating improvements in bone turnover a nd mineralization.