A SYNTHESIS OF ALPHA-CUPARENONE BASED ON SYMMETRY CONSIDERATIONS

Authors
HO TL CHANG MH
Citation
Tl. Ho et Mh. Chang, A SYNTHESIS OF ALPHA-CUPARENONE BASED ON SYMMETRY CONSIDERATIONS, Canadian journal of chemistry, 75(6), 1997, pp. 621-624
Citations number
7
Categorie Soggetti
Chemistry
Journal title
Canadian journal of chemistry → ACNP
ISSN journal
00084042
Volume
75
Issue
6
Year of publication
1997
Pages
621 - 624
Database
ISI
SICI code
0008-4042(1997)75:6<621:ASOABO>2.0.ZU;2-E
Abstract
A ring expansion approach to alpha-cuparenone was accomplished in 5 or 6 steps. The key intermediate is 3-methyl-3-(4-methylphenyl)cyclobuta none, which was derived from a [2+2]cycloaddition of dichloroketene on a styrene derivative, followed by dechlorination.