Subendometrial contractility is not predictive for in vitro fertilization (IVF) outcome

Objectives The aim of the study was to investigate whether endometrial thic kness, endometrial pattern, endometrial movement and serum estradiol and pr ogesterone affect the outcome of in vitro fertilization. Methods Prospectively collected data of endometrial thickness, endometrial pattern and subendometrial activity were analyzed in 122 consecutive in vit ro fertilization cycles. All measurements were made on the day of hCG admin istration (day -2), day of embryo transfer (day +2), day +6 and day +12. Results It would appear that pregnant women tend To have a thicker endometr ium on day +12 than non-pregnant women. There appears to be no appreciable difference between pregnant and non-pregnant women in endometrial movement and thickness, nor in serum estradiol and progesterone on day +2 and day +6 . In combining three echographic variables (thickness, pattern and movement ) and hormone level (estradiol and progesterone), only progesterone on day +12 could be used to predict the outcome. Conclusions Subendometrial contractility plays no important role in implant ation on the day of embryo transfer or 4 days later.