Familial recurrence of spontaneous fetal intracranial hemorrhage: ultrasonographic diagnosis and postnatal magnetic resonance imaging (MRI)

We report fetal intracranial hemorrhage in term siblings from consanguineou s parents, spontaneously occurring in the third trimester of pregnancy. Pre natal ultrasound in one case and postnatal MRI in both demonstrated massive parenchymal bleeding involving large areas of the cerebral cortex, white a nd gray matter. Vasculopathies, vascular malformations, coagulopathies, thr ombocytopenia and relevant metabolic disorders could be excluded.