Nc. Dean et al., Decreased mortality after implementation of a treatment guideline for community-acquired pneumonia, AM J MED, 110(6), 2001, pp. 451-457
Citations number
32
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
PURPOSE: We developed a pneumonia guideline at Intermountain Health Care th
at included admission decision support and recommendations for antibiotic t
iming and selection, based on the 1993 American Thoracic Society guideline.
We hypothesized that guideline implementation would decrease mortality.
SUBJECTS AND METHODS: We included all immunocompetent patients >65 years wi
th community-acquired pneumonia from 1993 through 1997 in Utah; nursing hom
e patients were excluded. We compared 30-day mortality rates among patients
before and after the guideline was implemented, as well as among patients
treated by physicians who did not participate in the guideline program.
RESULTS: We observed 28,661 cases of pneumonia, including 7,719 (27%) that
resulted in hospital admission. Thirty-day mortality was 13.4% (1,037 of 7,
719) among admitted patients and 6.3% (1,801 of 28,661) overall. Mortality
rates (both overall and among admitted patients) were similar among patient
s of physicians affiliated and not affiliated with Intermountain Health Car
e before the guideline was implemented. For episodes that resulted in hospi
tal admission after guideline implementation, 30-day mortality was 11.0% am
ong patients treated by Intermountain Health Care-affiliated physicians com
pared with 14.2% for other Utah physicians. Analysis that adjusted by logis
tic regression for age, sex, rural versus urban residences, and year confir
med that 30-day mortality was lower among admitted patients who were treate
d by Intermountain Health Care-affiliated physicians (odds ratio [OR]: 0.69
; 95% confidence interval [CI]: 0.49 to 0.97; P = 0.04) and was somewhat lo
wer among all pneumonia patients (OR: 0.81;95% CI: 0.63 to 1.03; P = 0.08).
CONCLUSION: Implementation of a pneumonia practice guideline in the Intermo
untain Health Care system was associated with a reduction in 30-day mortali
ty among elderly patients with pneumonia. (C) 2001 by Excerpta Medica, Inc.