A comparison of 0.0625% bupivacaine with fentanyl and 0.1% ropivacaine with fentanyl for continuous epidural labor analgesia

Citation
J. Fernandez-guisasola et al., A comparison of 0.0625% bupivacaine with fentanyl and 0.1% ropivacaine with fentanyl for continuous epidural labor analgesia, ANESTH ANAL, 92(5), 2001, pp. 1261-1265
Citations number
20
Categorie Soggetti
Aneshtesia & Intensive Care","Medical Research Diagnosis & Treatment
Journal title
ANESTHESIA AND ANALGESIA
ISSN journal
00032999 → ACNP
Volume
92
Issue
5
Year of publication
2001
Pages
1261 - 1265
Database
ISI
SICI code
0003-2999(200105)92:5<1261:ACO0BW>2.0.ZU;2-B
Abstract
We compared the analgesic efficacy and the degree of motor block achieved w ith epidural infusion of 0.0625% bupivacaine (Group B) versus 0.1% ropivaca ine (Group R), both with 0.0002% fentanyl (2 mug/mL) in laboring patients. A prospective, double-blinded study was performed in 98 ASA physical status I-IT parturients who were divided randomly into two groups to receive eith er bupivacaine or ropivacaine after catheter location had been tested with an initial bolus of lidocaine and fentanyl. The infusion rate was 15 mL/h i n every case. When pain was perceived, 5-mL boluses of the assigned epidura l analgesic were administered every 10 min until analgesia was achieved. We recorded pain intensity, level of sensory block, degree of motor block, he modynamic variables, secondary effects, mode of delivery, neonatal outcome, and patient satisfaction. There were no statistically significant differen ces in any of the factors analyzed. Highly effective analgesia was achieved in both groups with a small incidence of motor block. These findings sugge st that bupivacaine may be more potent than ropivacaine.