Aa. Den Broeder et al., Isolated digital vasculitis in a patient with rheumatoid arthritis: good response to tumour necrosis factor alpha blocking treatment, ANN RHEUM D, 60(5), 2001, pp. 538-539
Tumour necrosis factor alpha (TNF alpha) blocking agents are among the most
promising new treatments for rheumatoid arthritis (RA), However, no data e
xist about the effect of these agents on extra-articular manifestations of
RA. A patient is described with small vessel vasculitis that repeatedly res
ponded well to treatment with the soluble p55 TNF alpha receptor fusion pro
tein Ro 45-2081 (lenercept).