During the last 2 decades, psychologists increasingly have studied human in
teraction in a social rather than in an asocial context. Although this ecol
ogical approach to the study of social interaction signifies the vitality o
f social psychology, the design and analysis of this research presents chal
lenges that are not encountered in an asocial context. This article surveys
a set of multiple interaction designs and associated analytic strategies t
hat permit estimation of individual and dyadic phenomena. In addition, new
analytic approaches to the hierarchically nested dyadic design (a special c
ase of the multiple interaction design) that is used in studies of personal
relationships and behavior genetics are discussed.