Expression of connexin 30 in the developing mouse cochlea

Authors
Xia, AP Katori, Y Oshima, T Watanabe, K Kikuchi, T Ikeda, K
Citation
Ap. Xia et al., Expression of connexin 30 in the developing mouse cochlea, BRAIN RES, 898(2), 2001, pp. 364-367
Citations number
17
Categorie Soggetti
Neurosciences & Behavoir
Journal title
BRAIN RESEARCH
ISSN journal
00068993 → ACNP
Volume
898
Issue
2
Year of publication
2001
Pages
364 - 367
Database
ISI
SICI code
0006-8993(20010420)898:2<364:EOC3IT>2.0.ZU;2-5
Abstract
Mutations in the GJB6 gene encodinp connexin 30 (Cx30) can cause dominant f orms of nonsyndromic deafness. By studying immunohistochemical localization of Cx30 in the mouse cochlea at different ages from 0 to 30 days after bir th, we found that the expression of Cx30 is nearly the same as that of Cx26 . These findings suggest that as weil as Cs26. Cx30 may also contribute to the generation and maturation of endocochlear potential. (C) 2001 Elsevier Science B.V. All rights reserved.