Linear IgA bullous dermatosis in a patient with renal cell carcinoma

Citation
Rif. Van Der Waal et al., Linear IgA bullous dermatosis in a patient with renal cell carcinoma, BR J DERM, 144(4), 2001, pp. 870-873
Citations number
36
Categorie Soggetti
Dermatology,"da verificare
Journal title
BRITISH JOURNAL OF DERMATOLOGY
ISSN journal
00070963 → ACNP
Volume
144
Issue
4
Year of publication
2001
Pages
870 - 873
Database
ISI
SICI code
0007-0963(200104)144:4<870:LIBDIA>2.0.ZU;2-6
Abstract
Linear IgA bullous dermatosis (LABD) is an autoimmune subepidermal bullous disease with heterogeneous clinical manifestations, characterized by linear deposition of IgA along the epidermal basement membrane zone. We report a patient with a metastasized renal cell carcinoma who developed an extensive blistering eruption. The lesions showed immunopathological findings charac teristic of LABD. The patient showed a fair response to prednisolone and da psone. Treatment to control the LABD was no longer required when interferon -alfa was started as palliative therapy for the metastasized renal cell car cinoma. The association of LABD and malignancies has been documented before and is not due to mere chance alone.