In the King Khalid University Hospital (Central Province) and King Fah
ad Hospital of the University (Eastern Province) Saudi Arabia, we iden
tified 64 infants with cholestasis. The causes of cholestasis were idi
opathic neonatal hepatitis in 29; extrahepatic biliary atresia in 17;
neonatal hepatitis secondary to Rubella and Cytomegalovirus in six and
four infants, respectively: paucity of intrahepatic bile ducts in six
and galactosaemia in two. The diagnosis was confirmed by liver biopsy
and/or operative cholangiography, in all infants.