A novel radical cyclization of 2-bromoindoles. Synthesis of hexahydropyrrolo[3,4-b]indoles

Authors
Gribble, GW Fraser, HL Badenock, JC
Citation
Gw. Gribble et al., A novel radical cyclization of 2-bromoindoles. Synthesis of hexahydropyrrolo[3,4-b]indoles, CHEM COMMUN, (9), 2001, pp. 805-806
Citations number
30
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
9
Year of publication
2001
Pages
805 - 806
Database
ISI
SICI code
1359-7345(2001):9<805:ANRCO2>2.0.ZU;2-5
Abstract
Hexahydropyrrolo[3,4-b]indoles 6, 10, and 13 are obtained from 2-bromo-3-ca rboxamides 5, 9, and 12, respectively, by a 1,5-radical translocation proce ss followed by 5-endo-trig cyclization to the indole C-2 position.