A 5-year-old spayed ferret was presented for examination of a 0.5 x 0.5-cm
mass in the right perianal area. Cytologic examination of a fine-needle asp
irate of the mass revealed a likely diagnosis of carcinoma. Rapid growth of
the mass precluded surgical resection; therefore, a definitive course of r
adiation therapy was initiated. The mass recurred several times at secondar
y sites and was later diagnosed as an apocrine gland tubular adenocarcinoma
. A combination of surgery and radiation therapy was used to manage the mas
s and regional lymph node metastases.