We review some of the applications of submillimetre instruments for astrono
my and Earth atmospheric sciences where helium sorption refrigerators have
been used. We describe a three-stage helium refrigerator which uses a He-4-
He-3 double-stage refrigerator to precool and intercept the parasitic heatl
oad on a final He-3 single-stage refrigerator. This multi-stage configurati
on permits operation of the refrigerator system without externally pumping
on a He-4 bath. This results in simpler integration with the instrument and
allows scientific observations to be more easily made. We have achieved a
base temperature of 234 mK for a hold time of 20.4 h. The heat Lift at 280
mK is 15 muW. (C) 2001 Elsevier Science Ltd. All rights reserved.