Viral hepatitis constitutes the most common entity seen in hepatology pract
ice. Hepatitis A vaccination is recommended for patients with chronic hepat
itis. Both lamivudine and interferon are established therapies against chro
nic hepatitis B, with other treatments not equally effective. Adefovir dipi
voxil is a promising new treatment for lamivudine-resistant hepatitis B mut
ants. Lamivudine and hepatitis B immunoglobulin are effective in preventing
recurrence of hepatitis B after transplantation. The combination of interf
eron and ribavirin has been shown to be effective for treatment of hepatiti
s C. Studies support the antiviral, antifibrotic, and antineoplastic effect
of interferon therapy. Recurrence of hepatitis C after transplantation has
been associated with more rapid progression to cirrhosis, Other major adva
nces in the field of viral hepatitis during the past year are highlighted.
Curr Opin Gastroenterol 2001, 17:262-267 (C) 2001 Lippincott Williams & Wil
kins, Inc.