In vivo, systematic desensitization has been effective in the treatment of
agoraphobia. Currently, computer and display technology allow the creation
of virtual reality environments. Virtual reality therapy (VRT), based on th
is sophisticated technology, has been used in the treatment of subjects who
have been diagnosed with agoraphobia, a disorder that is defined as an ext
reme, irrational fear of being in places or situations from which escape mi
ght be difficult or embarrassing. These studies, however, are limited in sc
ope, having been conducted by using subjective tools to measure the effecti
veness of therapy. The goal of this study was to evaluate the effectiveness
of VRT by using not only the subjective tools but also several objective o
nes, such as blood pressure, respiration, and heart rate. A virtual environ
ment tunnel scene with traffic jam was created for this study; this scene w
as rated as one of the most fearful situations for our patients. The study
included seven subjects who were diagnosed with panic disorder with agoraph
obia using the Diagnostic and Statistical Manual of Mental Disorders (DSM-I
V) criteria. The data failed to support the efficacy of the objective measu
res. Improving the immersion process and the objective measures for evaluat
ing the effectiveness of VRT for agoraphobics appears to be a reasonable re
search strategy.