Perilymphatic pressure measurement in patients with Meniere's disease

The MMS-10 Tympanic Displacement Analyser is a new device for measuring per ilymphatic pressure in humans. This instrument was used in 70 patients with Meniere's disease (44 affected ears) and a group of 50 young normal hearin g subjects. No significant differences in perilymphatic pressure measuremen ts were found between the groups, Although measurement parameters showed la rge inter-individual variation in a subgroup of 25 patients, the intra-indi vidual correlation in the subgroup was good. In patients with Meniere's dis ease no relationship was found between perilymphatic pressure, hearing thre sholds, blood pressure, gender or age. There was no difference between unil aterally and bilaterally affected patients.