The influence of food bolus consistency on the pharyngeal wave during swall
owing was investigated using a four-sensor manometry probe in 22 healthy vo
lunteers. Pharyngeal pressures were recorded for 5 ml boluses of water, pud
ding and buttered bread via a manometry probe placed transnasally. The dist
al sensor was sited within the upper oesophageal sphincter (UOS); the three
proximal sensors were then located 2, 4 and 6 cm above the UOS. The amplit
ude and timing of the swallow waveforms for pudding and buttered bread were
recorded and compared with those for water. Increased bolus viscosity led
to increased amplitude of the bolus wave and clearing contraction within th
e pharynx. In the UOS, increased bolus viscosity was associated with a larg
er pressure nadir (sub-atmospheric pressure) on opening and intra bolus pre
ssure during transit. Bolus consistency also influenced the coordination of
the swallow response with delayed pharyngeal clearance. The putative relev
ance of these findings to dietary modification fur patients with neurologic
al and neuromuscular dysphagia is discussed.