Fruit and vegetable intake and population glycosylated haemoglobin levels:the EPIC-Norfolk Study

Objective: To investigate whether self-reported frequency of fruit and vege table consumption was associated with HbA(1C) levels in individuals not kno wn to have diabetes, and what dietary: and lifestyle factors might explain this association. Design: cross-sectional study. Setting: Thr EPIC-Norfolk Study, a population-based cohort study of diet an d chronic disease, Subjects and methods: A total of 2678 men and 3318 women (45-74 y) not know n to have diabetes reported weekly consumption of fruit, green leafy vegeta bles and other vegetables, Results: Among men, 274 (10.2%) reported seldom or never eating fruit and 1 27 (4,7%) seldom or never eating green leafy vegetables. Corresponding numb ers in women were 157 (4,7%) and 92 (2.8%). respectively. Participants who reported never or seldom having both fruit and green leafy vegetables had h igher mean (s,d.) HbA(1C) measurements (5.43% (0.71)) than those who report ed more frequent consumption (5.34% (0.67); P = 0.036). Differences by cate gory of fruit or preen leafy vegetable consumption were not substantially c hanged after adjustment for saturated fat. dietary fibre and plasma vitamin C. Conclusion: These findings support the hypothesis that high intake of fruit and green leafy; vegetables may influence glucose metabolism independent o f dietary fibre or vitamin C alone and that increased consumption may contr ibute to the prevention of diabetes.