Effects of subinhibitory concentrations of nitroxoline on the surface properties of Escherichia coli

Authors
Latrache, H Bourlioux, P Karroua, M Zahir, H Hakkou, A
Citation
H. Latrache et al., Effects of subinhibitory concentrations of nitroxoline on the surface properties of Escherichia coli, FOL MICROB, 45(6), 2000, pp. 485-490
Citations number
38
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
FOLIA MICROBIOLOGICA
ISSN journal
00155632 → ACNP
Volume
45
Issue
6
Year of publication
2000
Pages
485 - 490
Database
ISI
SICI code
0015-5632(2000)45:6<485:EOSCON>2.0.ZU;2-C
Abstract
Nitroxoline (5-nitro-8-quinolinol; NIQ) at subinhibitory concentrations (su b-MIC) decreased the adherence of uropathogenic Escherichia coli to cathete r surface and significantly enhanced cell surface hydrophobicity. The surfa ce hydrophobicity increased in the presence of sub-MIG of NIQ and also in a n excess of Mg2+. The effect of NIQ on the cell surface was not related to the bacteriostatic effect of this agent. The increase in nitrogen and decre ase in phosphate content in the cell surface was found in the presence of N IQ. NIQ did not inhibit the expression of fimbriae.