Complementary measures used by patients with gynecologic cancers undergoing cytotoxic or hormonal chemotherapy

Objective: We aimed at assessing the use of complementary modalities by pat ients with gynecologic cancers. Methods: A total of 215 unselected patients undergoing cytotoxic or hormona l chemotherapy for gynecologic malignancies were interviewed regarding thei r use of complementary or alternative treatments. Results: A total of 49 % of the interviewed patients used one or more compl ementary methods and almost a third used three or more. Combined formulatio ns included beetroot, enzymes, iron, alcohol and ascorbic acid most commonl y. The use of vitamin capsules appears questionable because the bioavailabi lity of several vitamins depends on the concomitant intake of fruits and ve getables. In contrast to vitamin capsules alone, fruits and vegetables have favorable effects on bowel motility. Several enzymes can cause gastrointes tinal side effects. Complications of mistletoe injections include a delay o f planned standard therapy. On the other hand, complementary measures may b e beneficial for selected patients. Positive psychologic effects, selenium supplementation or increased fluid intake may be beneficial. Conclusion: A working knowledge of complementary measures is important to b e able to discuss risks and benefits with patients. Alternative therapies s hould meet the standards required of other treatments, i.e., they should be effective, safe and of high pharmacologic quality.