Assisted reproductive technologies in conjunction with conservatively treated endometrial adenocarcinoma - A case report

This case report illustrates the successful use of assisted reproductive te chnologies (ARTs) in a patient receiving conservative treatment for endomet rial adenocarcinoma. A 31-year-old infertile woman, diagnosed as FIGO stage la endometrial adenocarcinoma (grade 1), received oral medroxyprogesterone acetate 400 mg/day for 12 weeks. Endometrial curettage was performed and t he absence of endometrial carcinoma was confirmed, A single pregnancy was a chieved with in vitro fertilization and embryo transfer. A healthy female i nfant was born via cesarean section at 42 weeks' gestation, The carcinoma h as not recurred, and the patient now desires a second child, We conclude th at ART combined with progesterone treatment might be a powerful option for the treatment of infertile patients with early stage, well-differentiated e ndometrial adenocarcinoma, Copyright (C) 2001 S. Karger AG, Basel.