Sd. Chen et al., Evidence of gallbladder function changes in hepatoma after transcatheter arterial embolization by quantitative Tc-99m DISIDA cholescintigraphy, HEP-GASTRO, 48(38), 2001, pp. 393-396
Background/Aims: Transcatheter arterial embolization is the treatment of ch
oice for inoperable hepatocellular carcinoma. Gallbladder infarction follow
ing transcatheter arterial embolization has been reported, therefore, the g
allbladder functions were studied using the quantitative Tc-99m DISIDA chol
eseintigraphy in the present study.
Methodology: The gallbladder functions which were presented as the filling
fraction and the ejection fraction in 24 patients with hepatoma before and
after transcatheter arterial embolization. The patients were separated into
two groups. Group 1: 12 patients received precystic artery transcatheter a
rterial embolization and group 2: 12 patients received postcystic artery tr
anscatheter arterial embolization.
Results: After transcatheter arterial embolization, significantly decreased
both gallbladder functions of filling fraction (61.2 +/-7.4% and 48.3 +/-6
.5%) and ejection fraction (47.8 +/-6.0% and 36.5 +/-5.3%) were found in gr
oup 1 patients. However, no significant change of filling fraction (59.0 +/
-5.0% and 58,8 +/-7.4%) and ejection fraction (49.9 +/-2.4% and 49.3 +/-5.7
%) in group 2 patients.
Conclusions: Impaired gallbladder functions were common in hepatoma patient
s who received precystic artery transcatheter arterial embolization, and Tc
-99m DISIDA cholescintigraphy may be useful for evaluating the gallbladder
functions in hepatoma patients who received transcatheter arterial emboliza
tion.