Modelling a binuclear metal binding site in the photosynthetic reaction centre II

Citation
Ls. Rath et Mk. Raval, Modelling a binuclear metal binding site in the photosynthetic reaction centre II, I J BIOCH B, 38(1-2), 2001, pp. 75-77
Citations number
24
Categorie Soggetti
Biochemistry & Biophysics
Journal title
INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS
ISSN journal
03011208 → ACNP
Volume
38
Issue
1-2
Year of publication
2001
Pages
75 - 77
Database
ISI
SICI code
0301-1208(200102/04)38:1-2<75:MABMBS>2.0.ZU;2-Z
Abstract
Based on the experimental data and homologous sites in Protein Data Bank (P DB) a model for metal binding sites in D1/D2 heterodimer has been proposed. On searching for tetranuclear and binuclear Mn binding sites in the PDB, a suitable sequence homology in thermolysin and D1 could be observed. From t he homology and site-directed mutagenesis data, a model for binuclear Mn-Ca or Mn-Mn has been built and it is extended to a tetranuclear Mn centre.