Mucinous cystadenoma coexisting with stromal tumor with minor sex-cord elements of the ovary: A case report

Mucinous neoplasms occur rarely in association with cystic teratoma, Sertol i-Leydig cell tumor, granulosa cell tumor or carcinoid tumor. Several cases of an ovarian stromal tumor with minor sex-cord elements have been reporte d in the literatures. However, there has been no report about an ovarian mu cinous neoplasm coexisting with a stromal tumor with sex-cord elements yet. We report a case of an ovarian neoplasm composed of both mucinous cystaden oma and stromal tumor with minor sex-cord elements in a 58-yr-old female. T he ovary including the mass measured 5 cm in size. On section, it revealed an unilocular cyst (4.5 cm in diameter) filled with mucinous fluid. There w as a round, yellow, solid nodule, 1.5 cm in diameter within the wall. Micro scopically, the cyst was lined by a single layer of endocervical mucinous e pithelium and the nodule was composed of spindle cells showing an intersect ing and whorled arrangement. There were cell nests showing polygonal shape with abundant cytoplasm among the spindle cells. They showed immunoreactivi ty for inhibin and did not have any connection with the adjacent mucinous e pithelium. Therefore, we interpret the mucinous cystadenoma as having arise n de novo.