Hydrophilic magnetic latex for nucleic acid extraction, purification and concentration

Authors
Elaissari, A Rodrigue, M Meunier, F Herve, C
Citation
A. Elaissari et al., Hydrophilic magnetic latex for nucleic acid extraction, purification and concentration, J MAGN MAGN, 225(1-2), 2001, pp. 127-133
Citations number
14
Categorie Soggetti
Apllied Physucs/Condensed Matter/Materiales Science
Journal title
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
ISSN journal
03048853 → ACNP
Volume
225
Issue
1-2
Year of publication
2001
Pages
127 - 133
Database
ISI
SICI code
0304-8853(200104)225:1-2<127:HMLFNA>2.0.ZU;2-X
Abstract
Core-shell magnetic latex particles bearing poly(N-isopropylacrylamide) in the shell were prepared by encapsulation of magnetic core using a precipita tion polymerization process. The cationic character of the particles' surfa ce is favorable for nucleic acid adsorption-desorption by controlling the p H and salinity of the medium. The concentration process of nucleic acids wa s presented and proven using DNA as a model. (C) 2001 Elsevier Science B.V. All rights reserved.