A DNA array sensor utilizing magnetic microbeads and magnetoelectronic detection

Authors
Miller, MM Sheehan, PE Edelstein, RL Tamanaha, CR Zhong, L Bounnak, S Whitman, LJ Colton, RJ
Citation
Mm. Miller et al., A DNA array sensor utilizing magnetic microbeads and magnetoelectronic detection, J MAGN MAGN, 225(1-2), 2001, pp. 138-144
Citations number
10
Categorie Soggetti
Apllied Physucs/Condensed Matter/Materiales Science
Journal title
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
ISSN journal
03048853 → ACNP
Volume
225
Issue
1-2
Year of publication
2001
Pages
138 - 144
Database
ISI
SICI code
0304-8853(200104)225:1-2<138:ADASUM>2.0.ZU;2-T
Abstract
We describe a multi-analyte biosensor that uses magnetic microbeads as labe ls to detect DNA hybridization on a micro-fabricated chip. The beads are de tected by giant magnetoresistance (GMR) magnetoelcctronic sensors embedded in the chip. The prototype device is a tabletop unit containing electronics , a chip carrier with a microfluidic flow cell, and a compact electromagnet and is capable of simultaneous detection of eight different analytes. (C) 2001 Elsevier Science B.V. All rights reserved.