Comparison of different particles and methods for magnetic isolation of circulating tumor cells

Authors
Sieben, S Bergemann, C Lubbe, A Brockmann, B Rescheleit, D
Citation
S. Sieben et al., Comparison of different particles and methods for magnetic isolation of circulating tumor cells, J MAGN MAGN, 225(1-2), 2001, pp. 175-179
Citations number
9
Categorie Soggetti
Apllied Physucs/Condensed Matter/Materiales Science
Journal title
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
ISSN journal
03048853 → ACNP
Volume
225
Issue
1-2
Year of publication
2001
Pages
175 - 179
Database
ISI
SICI code
0304-8853(200104)225:1-2<175:CODPAM>2.0.ZU;2-B
Abstract
A more effective method for tumor cell separation from peripheral blood was established. The results of optimized magnetic particles verified by analy zing yield, purity and viability of isolated epithelial tumor cells were co mpared with a commercial kit for immunomagnetic cell separation. Porous sil ica particles of 230 nm were found to give best recovery rates and high via bility of extracted cells. (C) 2001 Elsevier Science B.V. All rights reserv ed.