Citation
W. Moller et al., Macrophage functions measured by magnetic microparticles in vivo and in vitro, J MAGN MAGN, 225(1-2), 2001, pp. 218-225
Citations number
15
Categorie Soggetti
Apllied Physucs/Condensed Matter/Materiales Science
Journal title
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
ISSN journal
03048853
→ ACNP
Volume
225
Issue
1-2
Year of publication
2001
Pages
218 - 225
Database
ISI
SICI code
0304-8853(200104)225:1-2<218:MFMBMM>2.0.ZU;2-Q
Abstract
Monodisperse ferrimagnetic iron-oxide particles of 1.4 mum geometric diamet
er were used to study alveolar macrophage functions (phagocytosis, phagosom
e transport) and cytoskeletal integrity in healthy subjects and in patients
with idiopathic pulmonary fibrosis as well as in cultured macrophages. Dys
functions in phagocytosis, in phagosome transport and cytoskeletal integrit
y correlated with an impaired alveolar clearance and could be induced in vi
tro by cytoskeletal drugs. (C) 2001 Elsevier Science B.V. All rights reserv
ed.