Characterization and MRI study of surfactant-coated superparamagnetic nanoparticles administered into the rat brain

Authors
Kim, DK Zhang, Y Kehr, J Klason, T Bjelke, B Muhammed, M
Citation
Dk. Kim et al., Characterization and MRI study of surfactant-coated superparamagnetic nanoparticles administered into the rat brain, J MAGN MAGN, 225(1-2), 2001, pp. 256-261
Citations number
15
Categorie Soggetti
Apllied Physucs/Condensed Matter/Materiales Science
Journal title
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
ISSN journal
03048853 → ACNP
Volume
225
Issue
1-2
Year of publication
2001
Pages
256 - 261
Database
ISI
SICI code
0304-8853(200104)225:1-2<256:CAMSOS>2.0.ZU;2-7
Abstract
A pre-clinical study has been carried out for the utilization of magnetite (Fe-3 O-4) nanoparticles as a diagnostic tracer for MRI. Surfactant-coated Fe3O4 nanoparticles have been synthesized by a chemical coprecipitation met hod with a narrow particle size of around 6 nm. Preliminary experiments dem onstrated the feasibility of using superparamagnetic Fe-3 O-4 nanoparticles as contrast agents in MR imaging. (C) 2001 Elsevier Science B.V. All right s reserved.