Genetic and environmental factors in conduct problems and adult antisocialbehavior among adult female twins

Citation
Rb. Goldstein et al., Genetic and environmental factors in conduct problems and adult antisocialbehavior among adult female twins, J NERV MENT, 189(4), 2001, pp. 201-209
Citations number
51
Categorie Soggetti
Psychiatry,Neurology,"Neurosciences & Behavoir
Journal title
JOURNAL OF NERVOUS AND MENTAL DISEASE
ISSN journal
00223018 → ACNP
Volume
189
Issue
4
Year of publication
2001
Pages
201 - 209
Database
ISI
SICI code
0022-3018(200104)189:4<201:GAEFIC>2.0.ZU;2-5
Abstract
Most twin and adoption studies of conduct problems have demonstrated modest genetic effects but substantial contributions of shared family environment . Conversely, most investigations have shown marked genetic influences but modest contributions of shared family environment in adult antisocial behav ior. However, most previous work has focused on male subjects. We obtained retrospective reports of DSM-III-R-defined conduct disorder (CD) and adult antisocial behaviors from a population-based sample of female-female twin p airs. Genetic and environmental contributions to conduct problems and adult antisocial behaviors were examined using polychoric correlation coefficien ts and univariate structural equation modeling. Statistically significant b ut modest heritability was observed for conduct problems. A small, statisti cally nonsignificant contribution of shared family environment to CD behavi or was also noted. Adult antisocial symptoms showed modest contributions of both additive genetic and shared family environmental factors. In both chi ldhood and adulthood, the largest influence on antisocial behavior was indi vidual-specific environment. Our findings support the importance of both ge netic and environmental factors in antisocial behavior among women as well as the possibility that the relative importance of each set of influences d iffers by sex in both childhood and adulthood.