Synthesis of substituted cyclopropanone acetals by carbometallation and its oxidative cleavage with manganese(IV) oxide and lead(IV) oxide

Authors
Nakamura, M Inoue, T Nakamura, E
Citation
M. Nakamura et al., Synthesis of substituted cyclopropanone acetals by carbometallation and its oxidative cleavage with manganese(IV) oxide and lead(IV) oxide, J ORGMET CH, 624(1-2), 2001, pp. 300-306
Citations number
19
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF ORGANOMETALLIC CHEMISTRY
ISSN journal
0022328X → ACNP
Volume
624
Issue
1-2
Year of publication
2001
Pages
300 - 306
Database
ISI
SICI code
0022-328X(20010401)624:1-2<300:SOSCAB>2.0.ZU;2-1
Abstract
A variety of substituted cyclopropanone acetals were prepared by the additi on of an organozine reagent or a Grignard reagent to a substituted cyclopro penone acetal. MnO2- or PbO2-mediated oxidative ring opening reaction of th e substituted cyclopropanone acetals affords beta -alkoxyesters and protect ed beta -aminoesters with high efficiency. (C) 2001 Elsevier Science B.V. A ll rights reserved.