Synthesis of (-)-coniine and (-)-pipecoline using ruthenium catalyzed ringclosing metathesis

Authors
Pachamuthu, K Vankar, YD
Citation
K. Pachamuthu et Yd. Vankar, Synthesis of (-)-coniine and (-)-pipecoline using ruthenium catalyzed ringclosing metathesis, J ORGMET CH, 624(1-2), 2001, pp. 359-363
Citations number
39
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF ORGANOMETALLIC CHEMISTRY
ISSN journal
0022328X → ACNP
Volume
624
Issue
1-2
Year of publication
2001
Pages
359 - 363
Database
ISI
SICI code
0022-328X(20010401)624:1-2<359:SO(A(U>2.0.ZU;2-3
Abstract
Ring closing metathesis employing the well-known Grubbs' ruthenium catalyst has been used as the key step in the synthesis of piperidine alkaloids, (- )-coniine and (-)-pipecoline, and the asymmetric induction has been perform ed by using (R)-alpha -methyl benzylamine as an auxiliary. (C) 2001 Elsevie r Science B.V. All rights reserved.