Versatile palladium-catalyzed arylation of organomanganese chlorides by aryl bromides

In THF, a palladium-catalyzed cross-coupling reaction of organomanganese re agents with various aryl bromides including unreactive deactivated or hinde red aryl bromides was performed successfully in the presence of a new catal ytic system 1% PdCl2(dppp)-four equivalents DME. The scope of the reaction is very broad since many functional groups are tolerated, moreover, even hi ndered O,O ' -di- or trisubstituted diaryls were obtained in E;igh yields. It is interesting to note that hindered aryl bromides are more reactive tha n the corresponding aryl iodides. Alkyl, alkenyl and alkynylmanganese chlor ides also react under similar conditions. (C) 2001 Elsevier Science B.V. Al l rights reserved.