fMRI auditory language differences between dyslexic and able reading children

During fMRI, dyslexic and control boys completed auditory language tasks (j udging whether pairs of real and/or pseudo words rhymed or were real words) in 30s 'on' conditions alternating with a 30s 'off' condition (judging whe ther tone pairs were same). During phonological judgment, dyslexics had mor e activity than controls in right than left inferior temporal gyrus and in left precentral gyrus. During lexical judgment, dyslexics were less active than controls in bilateral middle frontal gyrus and more active than contro ls in left orbital frontal cortex. Individual dyslexics were reliably less active than controls in left insula and left inferior temporal gyrus. Dysle xic and control children differ in brain activation during auditory languag e processing skills that do not require reading. NeuroReport 12:1195-1201 ( C) 2001 Lippincott Williams & Wilkins.