Isolation of virus-cell fusion inhibitory components from Eugenia caryophyllata

Authors
Kim, HJ Lee, JS Woo, ER Kim, MK Yang, BS Yu, YG Park, H Lee, YS
Citation
Hj. Kim et al., Isolation of virus-cell fusion inhibitory components from Eugenia caryophyllata, PLANTA MED, 67(3), 2001, pp. 277-279
Citations number
13
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PLANTA MEDICA
ISSN journal
00320943 → ACNP
Volume
67
Issue
3
Year of publication
2001
Pages
277 - 279
Database
ISI
SICI code
0032-0943(200104)67:3<277:IOVFIC>2.0.ZU;2-X
Abstract
The fractionation of Eugenia caryophyllata (Myrtaceae) guided by the syncyt ia formation inhibition assay led to the isolation of four tannins (eugenii n, casuarictin. 1.3-di-O-galloyl-4,6-(S)-hexahydroxydiphenoyl-beta -D-gluco pyranose and tellimagrandin I), and two chromones (biflorin and isobiflorin ). Among the isolated compounds, tellimagrandin (4) showed a significantly high inhibitory activity on the syncytia formation with an IC50 value of 16 .12 +/- 1.98 mug/ml.