New indications for ivermectin

Introduction. - Ivermectin is a semi-synthetic derivative of a family of ma crocyclic lactones. This drug has a broad-spectrum anti-parasitic effect ag ainst various nematodes and ectoparasites. Current knowledge and key-points. - Onchocerciasis and lymphatic filariasis are common indications. More recently ivermectin has been recommanded in t he treatment of strongyloidiasis and scabies. Future prospects and projects. - Promising results have been shown in the t reatment of ascariasis, cutaneous larva migrans, loiasis and head lice. (C) 2001 Editions scientifiques et medicales Elsevier SAS.