Synthesis of 2-C-trifluoromethyl substituted D-ribose

Authors
Eilitz, U Bottcher, C Sieler, J Gockel, S Haas, A Burger, K
Citation
U. Eilitz et al., Synthesis of 2-C-trifluoromethyl substituted D-ribose, TETRAHEDRON, 57(18), 2001, pp. 3921-3925
Citations number
28
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
18
Year of publication
2001
Pages
3921 - 3925
Database
ISI
SICI code
0040-4020(20010430)57:18<3921:SO2SD>2.0.ZU;2-V
Abstract
A stereoselective three step synthesis of 2-C-trifluoromethyl D-ribose via McMurry pinacol cross coupling of 2,3-di-O-isopropylidene D-glyceraldehyde and methyl trifluoropyruvate is described. (C) 2001 Elsevier Science Ltd. A ll rights reserved.