Crystallization-induced asymmetric transformations and self-regeneration of stereocenters (SROSC): enantiospecific synthesis of alpha-benzylalanine and hydantoin BIRT-377

Authors
Napolitano, E Farina, V
Citation
E. Napolitano et V. Farina, Crystallization-induced asymmetric transformations and self-regeneration of stereocenters (SROSC): enantiospecific synthesis of alpha-benzylalanine and hydantoin BIRT-377, TETRAHEDR L, 42(18), 2001, pp. 3231-3234
Citations number
20
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
18
Year of publication
2001
Pages
3231 - 3234
Database
ISI
SICI code
0040-4039(20010430)42:18<3231:CATASO>2.0.ZU;2-7
Abstract
N-lsobutoxycarbonyl protected L-alanine was condensed with 4-phenylbenzalde hyde in a crystallization-controlled process to give the corresponding c is -oxazolidinone derivative as the sole product in high yield this underwent enolization and benzylation with the typical high degree of stereoselectivi ty observed in the SROSC involving this class of compounds. (C) 2001 Elsevi er Science Ltd. All rights reserved.