Syncopes are caused by a wide variety of diseases of the nervous system and
the heart. Suggesting cardiac causes of syncopes, the most important diffe
rential diagnosis are bradycardia (including pacemaker malfunction), tachyc
ardia, valvular heart diseases, heart failure due to coronary artery diseas
e with or without infarction, hypertension, myocarditis or cardiomyopathy.
Atrial fibrillation is associated with neurological events, systemic emboli
probably arising in the left ventricle must be suspected after myocardial
(mural thrombus) or in case of severe left ventricular dysfunction. Many di
agnostic tests are available for elevation of syncope: electrocardiogram, H
olter monitoring from 24 to 72 hours, echocardiography (including transesop
hageal echocardiography). Upright tilt testing may be useful in evaluation
of recurrent syncope of unknown cause in patients without organic heart dis
ease. If symptoms are recurrent but too infrequent for Hotter monitoring te
chniques an implantable loop recorder is useful in detecting dysrhythmias.