Intense hemosiderin deposits in a case of self-healing congenital histiocytosis.

Background, Congenital self healing histiocytosis, described for the first time in 1973 by Hashimoto and Pritzker, is characterized by multiple violac eous brown cutaneous papulonodules present at birth and disappearing sponta neously in 2 to 4 months, There are classically no systemic manifestations and the prognosis is always good. We present a case, particular by the inte nsity of hemosiderinic deposits. Case-report. The patient was a 2-month-old female infant. Physical examinat ion at birth revealed a healthy-appearing full-term newborn, with live skin lesions: firm violaceous-reddish pigmented papules and nodules distributed over the head (scalp and forehead), right ear, right forearm and the flexu ral aspect of the left thigh. There was no hepatosplenomegaly or lymphadeno pathy, and the patient's general condition was excellent. Histologic examin ation confirm the diagnosis by showing a dense polymorphous infiltrate comp osed of histiocytes associated with giant cells and erythrocytes extravasat ion. Perls stain was strongly positive. Staining with S100 Protein was posi tive. Outcome was good with involution of all lesions with atrophic and pig mented scan. Discussion. The patient's excellent general condition, the absence of visce ral locations and the spontaneous self healing allows us to classify this f orm as a benign self healing congenital histiocytosis. This patient present ed intensely hemosiderinic deposits giving the lesions a strongly pigmented aspect.