The genomic structure of SYCP3, a meiosis-specific gene encoding a proteinof the chromosome core

Authors
Botelho, RJ DiNicolo, L Tsao, N Karaiskakis, A Tarsounas, M Moens, PB Pearlman, RE
Citation
Rj. Botelho et al., The genomic structure of SYCP3, a meiosis-specific gene encoding a proteinof the chromosome core, BBA-GENE ST, 1518(3), 2001, pp. 294-299
Citations number
16
Categorie Soggetti
Molecular Biology & Genetics
Journal title
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
ISSN journal
01674781 → ACNP
Volume
1518
Issue
3
Year of publication
2001
Pages
294 - 299
Database
ISI
SICI code
0167-4781(20010416)1518:3<294:TGSOSA>2.0.ZU;2-Z
Abstract
SYCP3 localizes to the lateral elements of the synaptonemal complex and is essential for male meiosis. The genomic structure of SYCP3 consists of nine exons spanning approximately 14 kb. In mouse and rat, but not in hamster. the putative translation start of SYCP3 is present in the first exon. The p utative promoter of SYCP3 was also cloned and shown to drive transcription of a reporter gene in somatic cells. (C) 2001 Elsevier Science B.V, All rig hts reserved.