ZNF232: structure and expression analysis of a novel human C2H2 zinc finger gene(1), member of the SCAN/LeR domain subfamily

Authors
Mavrogiannis, LA Argyrokastritis, A Tzitzikas, N Dermitzakis, E Sarafidou, T Patsalis, PC Moschonas, NK
Citation
La. Mavrogiannis et al., ZNF232: structure and expression analysis of a novel human C2H2 zinc finger gene(1), member of the SCAN/LeR domain subfamily, BBA-GENE ST, 1518(3), 2001, pp. 300-305
Citations number
40
Categorie Soggetti
Molecular Biology & Genetics
Journal title
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
ISSN journal
01674781 → ACNP
Volume
1518
Issue
3
Year of publication
2001
Pages
300 - 305
Database
ISI
SICI code
0167-4781(20010416)1518:3<300:ZSAEAO>2.0.ZU;2-A
Abstract
We have identified a novel zinc finger gene, ZNF232, mapped to human chromo some 17p12. The coding region of the gene is organized in three exons corre sponding to a 417 amino acid long polypeptide containing a SCAN/LeR domain and five C2H2-type zinc fingers. ZNF232 is possibly a nuclear protein, as s uggested by expression analysis of GFP/ZNF232 chimeric constructs. ZNF232 t ranscripts were detected in a wide collection of adult human tissues. The g ene is possibly subjected to tissue-specific post-transcriptional regulatio n by means of alternative splicing. (C) 2001 Elsevier Science B.V. All righ ts reserved.