Recovery of erythropoiesis following allogeneic bone marrow transplantation for chronic lymphocytic leukaemia-associated pure red cell aplasia

Pure red cell aplasia is a rare condition, that can be either idiopathic or associated with a lymphoproliferative disorder. The latter is considered t o result from T cell-mediated suppression of haematopoiesis, and usually re sponds well to treatment with immunosuppressive medication. We describe a p atient with B-CLL-associated pure red cell aplasia who did not respond to s everal courses of immunosuppressive treatment. Erythropoiesis was finally r estored after allogeneic bone marrow transplantation.