Preliminary research on pulsed-electrospray phenomenon

A novel pulsed-electrospray device is reported in this paper. With such an apparatus, the observation of the electrospray process under the pulsed hig h voltage conditions has been successfully made with microscope, oscillosco pe and mass spectrometer. By using pulsed spray technique, the sample flow rate can be averagely decreased to < 100 nL/min. After increasing the frequ ency of pulsed high voltage, it is hopefully to directly combine this devic e to time-of-flight mass spectrometer and obtain a great enhancement both i n signal-to-noise ratio and in detection sensitivity for mass spectrometry analysis.