Separation of enantiomers on bovine serum albumin coated zirconia in reversed-phase liquid chromatography

Authors
Park, JH Ryu, JK Park, JK McNeff, CV Carr, PW
Citation
Jh. Park et al., Separation of enantiomers on bovine serum albumin coated zirconia in reversed-phase liquid chromatography, CHROMATOGR, 53(7-8), 2001, pp. 405-408
Citations number
20
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
CHROMATOGRAPHIA
ISSN journal
00095893 → ACNP
Volume
53
Issue
7-8
Year of publication
2001
Pages
405 - 408
Database
ISI
SICI code
0009-5893(200104)53:7-8<405:SOEOBS>2.0.ZU;2-I
Abstract
Zirconia is known to be one of the best materials for the chromatographic s upport due to its excellent chemical, thermal and mechanical stability. In this work we report preparation acid use of bovine serum albumin (BSA)-immo bilized zirconia as a chiral stationary phase for separation of some enanti omers in reversed-phase liquid chromatography. The BSA-zirconia showed good enantioselectivity for some of the enantiomers studied and could be used f or RPLC separations in mobile phases of alkaline pH.