Background and aims: This study was to review albumin prescriptions and ind
ications in 4122 patients hospitalized in internal medicine wards in the ye
ars 1996, 1998 and 1999, before and after the ad hoc regulations issued in
1997 by the Italian Ministry of Health.
Methods: In 1996 (n = 63), 1998 (n = 59) and 1999 (n = 55) 177 of these pat
ients (4.3%) were given i.v. albumin.
Results: 161 (91%) of them had serum albumin values of <3.5 g/dl, while in
only 36% were these values ( 2.5 g/dl.
Conclusion: In the majority of cases albumin was erroneously prescribed, of
ten to enhance diuretic efficacy or in protein energy malnutrition. its pre
sciption has not been influenced by the new recommendations. (C) 2001 Harco
urt Publishers Ltd.