The objective of the study was to evaluate the validity of oscillometric sy
stolic ankle pressure in symptomatic leg arterial occlusive disease. Ankle
pressure measurements using oscillometric curves obtained using a standard
12-cm cuff with a specially designed device for signal processing were vali
dated against the continuous wave (CW) Doppler technique. Thirty-four subje
cts without signs or symptoms of peripheral vascular disease (68 legs) and
17 patients with leg ischaemia (85 legs) varying from moderate claudication
to critical ischaemia were examined. The oscillometric curves were analyse
d using several algorithms reported in the literature, based on the assumpt
ion that maximum oscillations are recorded near mean arterial pressure. In
normals, reasonable agreement between CW Doppler and oscillometric methods
was seen. When an algorithm that determined the lowest cuff pressure at whi
ch maximum oscillations occurred, and a characteristic ratio for systolic p
ressure of 0.52 was used, the mean difference between CW Doppler and oscill
ometry was 1.7 mmHg [range -19 to +27, limits of agreement (2 SD) 21.1 mmHg
]. In ischaemic legs, oscillometry overestimated systolic ankle pressure by
a mean of 28.8 mmHg [range -126 to +65, limits of agreement 82.8 mmHg], Th
e difference was more pronounced among patients with critical ischaemia com
pared with claudicants, and also more evident among diabetics. The error of
oscillometric pressure determination in subjects with leg arterial disease
inversely increased with CW Doppler ankle pressure. In 39% of the recordin
gs in legs with a CW Doppler systolic pressure below 100 mmHg, the oscillom
etric mean arterial pressure was higher than the recorded CW Doppler systol
ic pressure. In conclusion, the oscillometric method to determine systolic
ankle pressure, based on the concept of maximum cuff oscillations occurring
near mean arterial pressure, is not reliable in leg arterial disease, usua
lly overestimating ankle pressure.