Mathematical methods to statistically compare the relative accuracy of phys
iological monitoring devices to reference measurements are scarce. We devel
oped such a method to compare any number of devices to each other as well a
s to reference values. This new statistical comparative procedure uses a co
mbination of different known mathematical processes. The method allows the
separation of the error of the devices into two components, the first, bein
g systematic, can be easily amended, while the second, inherent to the tech
nical limitations of the measuring device as well as to the physical proper
ties of the explored phenomenon, cannot be corrected and will thus be used
as the comparative criterion for statistics. That method, which is easy to
implement should ease comparisons of the accuracy of any number of devices
as well as comparison of other sets of physiological values, by giving an e
asy access to statistical results.