During the period of this review, there has been continued use and developm
ent of neuroimaging techniques in brain tumor diagnosis and management. Alt
hough no monumental developments or improvements in neuroimaging techniques
or technology have occurred, important studies continue to be published sh
owing the clinical impact and utility of various neuroimaging techniques to
improve the care of patients with brain tumors. Several studies have shown
the power of functional neuroimaging techniques with both magnetic resonan
ce imaging (MRI) and positron-emission tomography (PET) to map eloquent cor
tex and assist in the planning of surgical and radiation therapy. New nucle
ar imaging radiopharmaceuticals, including various PET ligands and single p
hoton emission computed tomography (SPECT) agents. have also been developed
and show their potential power in the evaluation of brain tumor patients.
New MRI pulse sequences to improve image quality and shorten imaging time h
ave also been developed. Several excellent reviews of the use of fluorodeox
yglucose (FDG)-PET and MRI techniques were also published. This article rev
iews the relevant and important neuroimaging literature related to brain tu
mor that was published during the defined time period of November 1, 1999 t
o October 31, 2000. Discussion is organized by modality, including nuclear
imaging techniques (SPECT and PET) and MRI (pulse sequence development, con
trast agent development, functional MRI developments, and general MRI-relat
ed information). Curr Opin Oncol 2001. 13:148-153 (C) 2001 Lippincott Willi
ams & Wilkins. Inc.